The seemingly invincible Spider-Man goes up against an all-new crop of villains—including the shape-shifting Sandman. While Spider-Man’s superpowers are altered by an alien organism, his alter ego, Peter Parker, deals with nemesis Eddie Brock and also gets caught up in a love triangle.
- Year: 2007
- Country: United States of America
- Genre: Fantasy, Action, Adventure
- Studio: Laura Ziskin Productions, Marvel Studios, Columbia Pictures
- Keyword: amnesia, dual identity, love of one's life, loss of loved one, forgiveness, hostility, superhero, sandstorm, spider, wretch, sand, narcissism, egomania, based on comic, sequel, revenge, symbiote
- Director: Sam Raimi
- Cast: Tobey Maguire, Kirsten Dunst, James Franco, Thomas Haden Church, Topher Grace, Bryce Dallas Howard