For years, Blade has fought against the vampires in the cover of the night. But now, after falling into the crosshairs of the FBI, he is forced out into the daylight, where he is driven to join forces with a clan of human vampire hunters he never knew existed—The Nightstalkers. Together with Abigail and Hannibal, two deftly trained Nightstalkers, Blade follows a trail of blood to the ancient creature that is also hunting him—the original vampire, Dracula.
- Year: 2004
- Country: United States of America
- Genre: Action, Horror, Fantasy
- Studio: Marvel Enterprises, New Line Cinema, Amen Ra Films, Imaginary Forces, Peter Frankfurt Productions
- Keyword: martial arts, loss of loved one, vampire, fbi, superhero, supernatural, fistfight, based on comic, vampire hunter (slayer), martial arts master, motorcycle, katana sword, blade, super villain, urban gothic, good versus evil
- Director: David S. Goyer
- Cast: Wesley Snipes, Jessica Biel, Ryan Reynolds, Kris Kristofferson, Dominic Purcell, Parker Posey